BACKGROUND Novel coronavirus disease (COVID-19) is spreading rapidly, which poses great challenges to patients on maintenance hemodialysis . Here we report the clinical features of 66 hemodialysis patients with laboratory confirmed COVID-19 infection .
PARTICIPANTS, AND MEASUREMENTS Retrospective, single-center case series of the 66 hemodialysis patients with confirmed COVID-19 from 1 January to 5 March 2020; the final date of follow-up was 25 March 2020 .
RESULTS The clinical data were collected from 66 hemodialysis patients with confirmed COVID-19 . The incidence of COVID-19 in our center was 11.0% (66/602), of which 18 patients died . According to different prognosis, hemodialysis patients with COVID-19 were divided into the survival and death group . A higher incidence of fever and dyspnea was found in the death group compared with the survival group . Meanwhile, patients in the death group were often accompanied by higher white blood cell count, prolonged PT time, increased D-dimer (< .05). More patients in the death group showed hepatocytes and cardiomyocytes damage . Furthermore, logistic regression analysis suggested that fever, dyspnea, and elevated D-dimer were independent risk factors for death in hemodialysis patients with COVID-19 (OR , 1.077; 95% CI , 1.014 to 1.439; = .044; OR , 1.146; 95% CI , 1.026 to 1.875; = .034, OR , 4.974; 95% CI , 3.315 to 6.263; = .007, respectively).
CONCLUSIONS The potential risk factors of fever, dyspnea, and elevated D-dimer could help clinicians to identify hemodialysis patients with poor prognosis at an early stage of COVID-19 infection.