Healthcare workers performing bronchoscopy, especially in urgent cases, may be at risk of aerosol-transmitted infection with severe acute respiratory syndrome coronavirus 2 . Therefore, such healthcare workers require thorough protection from aerosol droplets . To this end, we developed a novel handmade protective barrier enclosure for performing flexible bronchoscopy . The use of this enclosure did not entail any special technique for handling the bronchoscope during bronchoscopy . The enclosure may be helpful in protecting bronchoscopists from the risk of aerosol-transmitted infections, including coronavirus disease 2019.