BACKGROUND: The effect of the COVID-19 pandemic on people with Parkinson's disease (PD) is poorly understood .
OBJECTIVE: To rapidly identify areas of need and improve care in people with PD during the COVID-19 pandemic, we deployed a survey to assess COVID-19 symptoms and the pandemic's effect among those with and without COVID-19 .
METHODS: People with and without PD participating in the online study Fox Insight (FI) were invited to complete a survey between April 23 and May 23 , 2020 . Among people reporting COVID-19 diagnoses, we compared symptoms and outcomes in people with and without PD . Among people not reporting COVID-19, we assessed access to healthcare and services and PD symptoms .
RESULTS : 7,209/9,762 active FI users responded (approximately 74% response rate), 5,429 people with PD and 1,452 without PD . COVID-19 diagnoses were reported by 51 people with and 26 without PD . Complications were more frequent in people with longer PD duration . People with PD and COVID-19 experienced new or worsening motor (63 %) and nonmotor (75 %) symptoms . People with PD not diagnosed with COVID-19 reported disrupted medical care (64 %), exercise (21 %), and social activities (57 %), and worsened motor (43 %) and non-motor (52 %) symptoms . Disruptions were more common for those living alone, with lower income and non-white race .
CONCLUSIONS: The COVID-19 pandemic is associated with wide-ranging effects on people with PD, and certain groups may be at particular risk . FI provides a rapid, patient-centered means to assess these effects and identify needs that can be used to improve the health of people with PD.