We outline a context-centered therapy approach to helping clients cope with the coronavirus pandemic . Context-centered therapy is a constructivist approach that emphasizes shifts in an individual ’ s contexts as the best way to generate therapeutic change . Contexts are defined as sets of presuppositions that shape a person ’ s experiences . We examine how two very common contexts, mind and self, can inform therapists ’ understanding of how their clients are responding to the coronavirus pandemic . The mind consists of a person ’ s defensive and protective postures in the face of perceived threat, whereas the self takes a broader perspective and emphasizes human connections and interrelatedness . Therapists can use several mind/self contrasts—blame versus responsibility, insufficiency versus sufficiency, being at effect versus being at cause, and avoidance versus mastery—to assist people who are struggling in the face of the coronavirus pandemic.