Coronavirus disease (COVID-19) is an unprecedented pandemic . COVID-19 is a highly contagious and potentially fatal respiratory infection which has spread within three months of its outbreak to more than 173 countries, causing 3.7 million infections and 256,551 deaths at this writing . Unfortunately, no treatment or vaccine currently exists for COVID-19, although several clinical trials are on-going to find a definite solution to this pandemic . Prevention through public health measures remain the best strategy recommended till date . This prevention involves physical distancing and compulsory confinement at home in several European countries, in the UK and USA . Unfortunately, home confinement decreed in most high-income countries like France has been dangerous for women, victims of psychological, physical and sexual violence from their intimate partner . Violence between intimate partners has become an unintended consequence of the stay-at-home policy against COVID-19 . Since the promulgation of a home confinement decreed in many high resource settings (USA, UK, Europe, Canada, Australia, etc), the rate of violence between intimate partners has increased tremendously resulting to the worst scenario, women ’ s death in some of these countries . The stay-at-home law is not yet a national decree in several low resource settings like Africa, where COVID-19 has not been declared an epidemic in several countries . However, intimate partner violence has been reportedly described as a real violation of women ’ s right before the advent of the COVID-19 pandemic in the African continent . This commentary highlights the effects of intimate partner violence due to COVID-19 confinement in France and extrapolates what may be the effect of an implementation of a COVID-19 confinement law in Cameroon . Also, the authors suggest recommendations to lessen the burden of intimate partner violence in countries with a stay-at-home policy.