SARS-CoV-2 is a novel infectious agent that rapidly spread from a single city in China to all parts of the world . Right now, the world is facing a major pandemic crisis and every infected patient can infect the other two to three persons . The non-specific symptoms at the early stages of coronavirus 2019 (Covid-19) and also the presence of infected asymptomatic patients result in the absence of accurate estimation of infected patients . Although coronaviruses often affect the upper or lower respiratory tract, viral shedding in plasma or serum can occur and therefore, there is a theoretical risk regarding the transmission of these viruses by transfusion . Experience with other viruses from the corona family group (SARS-CoV and MERS-CoV) tells us that Covid-19 might have a significant impact on blood supply . Until now, SARS-CoV-2 has not been identified as a transfusion transmissible virus and viremia has only been diagnosed in serious patients who would not be allowed for blood donation . In this review article, the safety of blood products during the Covid-19 outbreak is discussed.