We report on a photobioelectrochemical fuel cell consisting of a glucose oxidase modified BiFeO 3 photobiocathode and a quantum dot sensitized inverse opal TiO 2 photobioanode linked to FAD glucose dehydrogenase via a redox polymer . Both photobioelectrodes are driven by enzymatic glucose conversion . Whereas the photobioanode can collect electrons from sugar oxidation at rather low potential, the photobiocathode shows reduction currents at rather high potential . The electrodes can be arranged sandwich-like due to the semi-transparent nature of BiFeO 3, which also guarantees a simultaneous excitation of the photobioanode when illuminated via the cathode side . This tandem cell can generate electricity under illumination and in the presence of glucose and provides an exceptionally high OCV of about 1 V. The developed semi-artificial system has significant implications on the integration of biocatalysts in photoactive entities for bioenergetic purposes and opens a new way for the generation of electricity from sun light and (bio-) fuels.