The novel Coronavirus, named SARS-COV-2, is responsible of the COVID-19 . It is a viral pneumonia that appeared in December 2019 in Wuhan, China, and is causing a pandemic . Most of patients present mild symptoms, but in many other patients, acute respiratory distress (ARDS) is more likely to be developped . The actual problematic is the appearance of cases with virus reactivation . We report a case of virus reactivation in a COVID-19 patient with ARDS.