Objective To evaluate the clinical and CT manifestations of coronavirus disease 2019 (COVID-19). Methods Serial clinical and CT data of 11 patients with confirmed COVID-19 were retrospectively analyzed . These data were collected in The Second Affiliated Hospital of Xi'an Jiaotong University from January 24 to February 9 , 2020 . There were 6 males and 5 females, aged from 17 to 64 years old, with the mean age of 42.27±15.67 . Results A majority of the patients fell into mild type and only one was of severe type . Clinical manifestations were mainly fever, fatigue, and dry cough . For laboratory tests, the patients' lymphocyte and eosinophil counts decreased, while their C-reactive protein concentration increased . In terms of CT findings , 7 patients showed bilateral subpleural involvement . The ground glass opacity (GGO) was common in CT findings . Typical crazy paving sign, air bronchogram and halo sign were also found . During the progression of the disease, GGO might be associated with pulmonary consolidation . No enlarged lymph nodes or pleural effusion were seen in all the patients . Conclusion Patients with COVID-19 have distinctly characteristic chest CT manifestations and laboratory examination findings, which play a vital role in diagnosis and prognosis of the disease.