The COVID-19 pandemic meant that the population-based colorectal cancer (CRC) screening programmes had to be suspended . In order to reduce SARS-CoV-2 transmission, modifications were made to the organization . We report the experience of the Galician CRC screening programme and patient safety results . Endoscopy was suspended between 13/03/2020 and 11/05/2020 . After resumption, a total of 3310 colonoscopies were performed (1702 positive faecal occult blood test , 1608 endoscopy monitoring). No SARS-CoV-2 infection was detected in the subsequent fortnight . Resumption of activity associated with population screening was safe.