Objective: To characterize health care-related adverse events in patients with SARS-CoV-2 infection who died in a tertiary hospital .

Methods: This is a retrospective, observational study, that included patients who died at HUGTiP hospital between 16 March and 10 April 2020 . Data was extracted from the electronic medical record .

Results: The median age of the 164 SARS-CoV-2 infected patients who died in the center in the study period was 77.5 years and> 90% of patients had ≥ 1 comorbidity . Forty point two percent of patients had at least ≥ 1 health care-related adverse event . Twenty three point eight of patients had an adverse drug reaction, the leading cause of adverse events in patients who died . Of patients who died in intensive care units, the frequency of problems related to mechanical ventilation was 8.8% .

Conclusions: Although the case fatality rate associated with the adverse events detected was very low, close monitoring of potential health care-related adverse events, especially drug reactions, as the therapeutic management of the disease remains unclear.