A 38-year-old man presented to emergency department with dizziness, dyspnea and diarrhea for 5 days . Serum lab data revealed lymphopenia and computed tomography imaging of the chest exhibited multiple ground-glass patches in bilateral lung fields . COVID-19 was suspected and further examination was done . But patient ’ s dyspnea progressed while waiting for the result of COVID-19 examination and respiratory failure with cardiac arrest occurred eventually, acute myocardial infarction was diagnosed then . This article is aimed to discuss the dilemmas in managing acute myocardial infarction during COVID-19 pandemic.