Coronavirus 2019 (COVID-19), caused by the pathogen SARS-CoV-2, was declared a pandemic in March 2020 . Recently, studies have discussed reports of patients infected with COVID-19 associated with vesicular manifestations of Herpes Zoster . The objective of this study was to compare the data from the Unified Health System (SUS), on the number of diagnoses of Herpes Zoster from March to September 2017 to 2019, with the same period of 2020, in the five Brazilian regions (North, Northeast, Southeast, South and Midwest). The analyzed data were extracted from the public database (DATASUS) of the Ministry of Health of Brazil . The data showed an increase in the number of Herpes Zoster diagnoses over the years, and the negative impact from the COVID-19 disease, revealing an increase corresponding to an average of over extra 10.7 cases per million of inhabitants during the COVID-19 pandemic in all Brazilian Regions . Therefore, although the association between HZ and COVID-19 is not well stablished, we observed in this study an increase in HZ cases during the COVID -19 pandemic, which suggests a correlation between these diseases.