The COVID-19 crisis led a group of scientific and informatics experts to accelerate development of an infrastructure for electronic data exchange for the identification, processing, and reporting of scientific findings . The Fast Healthcare Interoperability Resources (FHIR®) standard which is overcoming the interoperability problems in health information exchange was extended to evidence-based medicine (EBM) knowledge with the EBMonFHIR project . A 13-step Code System Development Protocol was created in September 2020 to support global development of terminologies for exchange of scientific evidence . For Step 1, we assembled expert working groups with 55 people from 26 countries by October 2020 . For Step 2, we identified 23 commonly used tools and systems for which the first version of code systems will be developed . For Step 3, a total of 368 non-redundant concepts were drafted to become display terms for four code systems (Statistic Type, Statistic Model, Study Design, Risk of Bias). Steps 4 through 13 will guide ongoing development and maintenance of these terminologies for scientific exchange . When completed, the code systems will facilitate identifying, processing, and reporting research results and the reliability of those results . More efficient and detailed scientific communication will reduce cost and burden and improve health outcomes, quality of life, and patient, caregiver, and healthcare professional satisfaction . We hope the achievements reached thus far will outlive COVID-19 and provide an infrastructure to make science computable for future generations . Anyone may join the effort at https: //www.gps.health/covid19_knowledge_accelerator.html.