In the present paper, we tested an objectification theory model including compliance with COVID-19 safety measures as an outcome . Safety measures recommended by governments and health organizations include monitoring one's body and interpersonal and social distance from others . We contend that the diffuse safety anxiety stemming from sexual and self-objectification encourages targets to broadly adopt behaviors that protect against body-based dangers, including COVID-19 . Accordingly, safety anxiety should predict greater compliance with COVID-19 safety measures . U.S. residents (N = 501) were recruited online and completed measures of sexual objectification, self-objectification, safety anxiety, appearance anxiety, and COVID-19 safety compliance . Two-step mediation analyses revealed a positive indirect effect of sexual objectification on safety anxiety through internalization of observers' perspectives (self-objectification Factor 1); in turn, there was a positive indirect effect of internalized others on COVID-19 body-based safety compliance through safety anxiety . Moreover, women (vs. men) reported higher levels of sexual objectification, internalization of observers' perspectives, safety anxiety, appearance anxiety, and COVID-19 safety measure compliance . Not only is safety anxiety relevant to cautionary behaviors protective against sexual objectification threat, but it also predicts compliance with measures that reduce the risk of contracting COVID-19 . Implications for objectification theory are discussed.