The Coronavirus Disease-19 (COVID-19), which spread to the world from Wuhan (China) in late December, was announced as a pandemic by the World Health Organization in March 2020 . In addition to acute respiratory syndrome symptoms, this virus also affects non-respiratory organs according to existing data . ACE 2 and TMPRSS2, that play a critical role in the entrance of SARS-COV-2 into the cell, are co-expressed in placental development stages so the placenta also carries a risk for this virus . Many studies have shown that this virus causes some histopathological changes in the placenta . The vertical transmission of the virus is not yet clear, but available data have shown that the indirect effects of the virus can be seen on the fetus . This paper focuses on revealing the effects of the virus on the placenta in all aspects . This article is protected by copyright . All rights reserved.