The number of scientists and correspondingly the flood of publications explode``Between 2008 and 2014, the number of scientific articles catalogued in the Science Citation Index of Thomson Reuters' Web of Science grew by 23% There were 7 8 million full-time equivalent researchers in 2013, representing growth of 21% since 2007``This has consequences to the rules of science production in the science factories Publica Publications are products that need marketing and the cash paid is a long list of publications and citations in journals of high impact factors that foster the career of authors Here, rules that will support the quality of science are highlighted It includes the need not to engage in innovative topics that have a high risk of failing and the importance to discuss work with colleagues in conferences and wherever possible