BACKGROUND: The COVID-19 pandemic has provided social isolation with a potential negative impact on the educational routine, including the suspension of face-to-face appointments, and mental health of medical students . The Mario Pinotti II study (MPII) is a 24-week observational study with scheduled telephone calls every 2 weeks to verify the occurrence of the COVID-19 in rheumatic patients on hydroxychloroquine chronically (from 29th, March , 2020 to 30th, September , 2020). The effects of voluntary participation in a research project, which foresees interaction by telephone contact with patients, professors, rheumatologists, and colleagues on the daily life and mental health of medical students requires evaluation .
OBJECTIVE: Considering that medical students are professionals in training with a high level of responsibility to handle emotional and physical aspects related to several diseases, this study has the aim of evaluating the impact of the COVID-19 pandemic and participation in the MPII study, on the educational routine and mental health of medical students .
METHODS: A web-based survey was carried out to perform a cross-sectional comparative assessment between medical students participating in the MPII study and other their colleagues who are not involved in this research project, matched to sex, age and medical school . The web questionnaire was developed by a panel composed of graduate medical students, rheumatologists, medical school professors, and a psychology professor and it included details on demographic and life habits data, as well as evaluation of participants' impression about the MPII study and the impact of the COVID-19 pandemic on their educational routine and medical training . In addition, the depressive, anxiety, and stress domains were evaluated using the DASS-21 (Depression, Anxiety and Stress Scale), Brazilian version, and, lately, the scores were grouped as low, moderate and high risk for mental distress . This project was approved by the Federal University of São Paulo Ethics Committee (CAAE : 34034620.0.0000.5505).
RESULTS: Data collection was applied for both medical student groups from July 20th to August 31st , 2020 . Data extraction was completed in September , 2020 . Analysis is ongoing . The authors expect the results to be published in the first semester of 2021 .
CONCLUSIONS: This study will bring light into the effects of participating in a research project on depressive, anxiety, and stress domains by using the DASS-21 (Depression, Anxiety and Stress Scale) in large sampling of Brazilian undergraduate medical students and the evaluation of the impact of the COVID-19 pandemic on students educational routine and medical training . CLINICALTRIAL: None.