During the pandemic, many healthcare professionals (HCPs) are overburdened by work and stress . The aim of the study was to examine alcohol intake, sleep disorders, and depressive symptoms of HCPs during the pandemic in comparison with the pre-pandemic period . Another goal was to indicate risk factors for mental state deterioration and an increase in alcohol use . A cross-sectional survey study was conducted from 1 April to 15 May 2020 . HCPs (n = 158) completed questionnaires that probed for symptoms during and prior to the pandemic, including the Beck depression inventory (BDI), Social Support Scale (MOS-SSS), Athens insomnia scale (AIS), and Alcohol Timeline Followback (TLFB) calendar of alcohol consumption . Gender, age, education, marital status, work situation, income, participants ’ and relatives ’ COVID-19 diagnosis as correlates were analyzed . Depressive symptoms and insomnia became more severe during the pandemic among HCPs, while social support increased . The increase in depressive symptoms was even higher among women (OR 2.78 , 95% CI 1.05–7.36; p = 0.04) and was also positively correlated with work reduction (p = 0.02); the presence of sleep disorders was correlated with female gender . Alcohol consumption increased during the pandemic, and was correlated with both more time spent at work and income increase . HCPs involved in the treatment of COVID-19 need support and attention due to the excessive stress load during pandemics, resulting in depression, insomnia, and increased alcohol intake.