Living with chronic kidney disease (CKD) is associated with hardships for patients and their care-partners . Empowering patients and their care-partners, including family members or friends involved in their care, may help minimize burden and consequences of CKD related symptoms to enable life participation . There is a need to broaden the focus on living well with kidney disease and re-engagement in life, including emphasis on patients being in control . The World Kidney Day (WKD) Joint Steering Committee has declared 2021 the year of``Living Well with Kidney Disease"in an effort to increase education and awareness on the important goal of patient empowerment and life participation . This calls for the development and implementation of validated patient-reported outcome measures to assess and address areas of life participation in routine care . It could be supported by regulatory agencies as a metric for quality care or to support labelling claims for medicines and devices . Funding agencies could establish targeted calls for research that address the priorities of patients . Patients with kidney disease and their care-partners should feel supported to live well through concerted efforts by kidney care communities including during pandemics . In the overall wellness program for kidney disease patients, the need for prevention should be reiterated . Early detection with prolonged course of wellness despite kidney disease, after effective secondary and tertiary prevention programs, should be promoted . WKD 2021 continues to call for increased awareness of the importance of preventive measures throughout populations, professionals and policy makers, applicable to both developed and developing countries.