Background: Acute respiratory illness caused by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) involved the whole globe within no time . Various studies published globally have shown variable severity of disease and mortality . The objective of our study was to describe clinical and epidemiological characteristics of the disease in our setup .
Methods: in this descriptive case series, individuals with signs and symptoms of Coronavirus disease-19 (COVID-19) and asymptomatic patients with history of close contact to confirmed COVID-19 patients were considered for SARS-CoV-2 Polymerase chain reaction (PCR) assay . Epidemiological and clinical features of only PCR positive cases were recorded . Data regarding hospitalization status, exposure to known COVID-19 patients, clinical feature and clinical outcome of patients was collected and interpreted .
Results: A total of 266 patients were found to be SARS-CoV 2 PCR positive which were included in the study . Mean age of patients was 39.45±31.9 years and majority of the patients in our study were male, i.e. , 238 (89.5 %). Most common clinical features among COVID-19 symptomatic patients were fever and dry cough followed by myalgias and sore throat . Eighteen (7 %) out of 266 died in our setup . Time duration of viral shedding after initial positive PCR varied between 11 days to up to more than 55 days . Conclusion: Coronavirus disease-19 (COVID-19) can present with wide range of clinical spectrum and disease can be life threatening . Severity of disease, requirement of ICU care and mortality were directly related to age of the patient and underlying comorbidities . Rigorous precautionary measures are of utmost importance particularly in this high-risk population.
Index: SARS-CoV-2; Coronavirus disease-19, COVID-19; Polymerase chain reaction, Severe Acute Respiratory Syndrome Coronavirus-2,