OBJECTIVE: Children are relatively protected from COVID-19, due to a range of potential mechanisms . We investigated if contact with children also affords adults a degree of protection from COVID-19 .
DESIGN: Cohort study based on linked administrative data .
SETTING: Scotland . STUDY POPULATION: All National Health Service Scotland healthcare workers and their household contacts as of March 2020 . MAIN EXPOSURE: Number of young children (0-11 years) living in the participant's household . MAIN
OUTCOMES: COVID-19 requiring hospitalisation, and any COVID-19 (any positive test for SARS-CoV-2) in adults aged ≥18 years between 1 March and 12 October 2020 .
RESULTS: 241 266, 41 198, 23 783 and 3850 adults shared a household with 0 , 1 , 2 and 3 or more young children, respectively . Over the study period, the risk of COVID-19 requiring hospitalisation was reduced progressively with increasing numbers of household children-fully adjusted HR (aHR) 0.93 per child (95% CI 0.79 to 1.10). The risk of any COVID-19 was similarly reduced, with the association being statistically significant (aHR per child 0.93; 95% CI 0.88 to 0.98). After schools reopened to all children in August 2020, no association was seen between exposure to young children and risk of any COVID-19 (aHR per child 1.03; 95% CI 0.92 to 1.14).
CONCLUSION: Between March and October 2020, living with young children was associated with an attenuated risk of any COVID-19 and COVID-19 requiring hospitalisation among adults living in healthcare worker households . There was no evidence that living with young children increased adults' risk of COVID-19, including during the period after schools reopened.
Index: COVID-19, epidemiology