Enterovirus A71 (EV-A71) is a major causative agent of hand, foot, and mouth disease (HFMD) and herpangina . Moreover, EV-A71 infection can lead to neurological complications and death . Vaccination is the most efficient way to control virus infection . There are currently three inactivated, whole EV-A71 vaccines licensed by the China NMPA (National Medical Products Administration). Several other types of vaccines, such as virus-like particles and recombinant VP1 (capsid protein), are also under development . In this review, we discuss recent advances in the development of EV-A71 vaccines.
Index: Enterovirus A71, Sinovac, foot and mouth disease (HFMD), hand, vaccine