PURPOSE: To elucidate the relationship between partial blink rate (PBR) and ocular surface parameters .
METHODS: We conducted a retrospective cross-sectional study of the patients who visited the Kim's Eye Hospital between March 2020 and July 2020 . Blinking dynamics, tear film lipid layer thickness (LLT), non-invasive tear film break- up time (NITBUT), tear meniscus height (TMH), and meibomian gland (MG) dropout rate were assessed using the IDRA ® Ocular surface analyzer (SBM SISTEMI, Inc., Torino, Italy) (IDRA). Dry eye symptoms were quantified by the Standard Patient Evaluation of Eye Dryness (SPEED) questionnaire scores .
RESULTS: A total of 47 non-Sjögren dry eye patients (47 right eyes, mean age = 56.8 ± 14.5 [20-75] years, 66% female) were enrolled . Among the ocular surface parameters, PBR had strong correlations with MG dropout rate (r = 0.811; p <0.01) and moderate correlations with SPEED scores (r = 0.596; p <0.01). MG dropout rate and age had moderate correlations with SPEED scores (r = 0.416; p = 0.04 and r = 0.322; p = 0.03, respectively). Comparisons by sex revealed no significant difference in characteristics, except for the TMH value . The TMH of female patients (0.17 ± 0.07) was significantly higher than that of males (0.14 ± 0.04; p = 0.04). LLT showed no significant correlation with the other variables .
CONCLUSION: PBR and MG dropout rates measured with IDRA were significantly correlated to dry eye symptoms.
Index: Blink, IDRA®, Interferometry, Lipid layer, Meibomian gland dysfunction