This paper presents a case of coinfection of influenza A virus (H1N1) and respiratory syncytial virus (RSV) in a male newborn . On the first day of life, the newborn required passive oxygen therapy, followed by respiratory support with nasal continuous positive airway pressure (nCPAP) due to respiratory insufficiency . As the newborn's respiratory effort was intensifying, he was intubated . In the second day of life, a nasopharyngeal swab was taken yielding the presence of H1N1 and RSV in the RT-PCR test . The child was isolated and given oseltamivir and empirical antibiotic therapy, which improved his condition . Other newborns who initially stayed with the sick child in the post-delivery room did not obtain oseltamivir prophylactically as their nasopharyngeal swabs were negative . The child's parents denied the occurrence of influenza-like symptoms within 14 days of delivery, which suggests a transplacental transmission of the child's infection or asymptomatic course of infection in the parents . In conclusion, this report confirms the possibility of viral coinfections in newborns, which points attention to considering a panel of respiratory viruses in the diagnostics . Symptoms of influenza in newborns may be atypical, including a fever-free course . Oseltamivir treatment in newborns with influenza seems an effective therapeutic measure.
MeSH: Coinfection, diagnosis, drug therapy, Humans, Infant, Infant, Newborn, Influenza A Virus, H1N1 Subtype, genetics, Influenza, Human, complications, diagnosis, drug therapy, Male, Respiratory Syncytial Virus Infections, complications, diagnosis, drug therapy, Respiratory Syncytial Virus, Human, Respiratory Tract Infections
Index: Coinfection, Influenza, Nasopharyngeal swab, Newborn, Respiratory syncytial virus