Coronavirus disease is characterized by an acute phase in which respiratory symptoms prevail and a post-acute phase in which symptoms are related to prolonged immobilization, respiratory dysfunctions, cognitive and emotional disorders . Therefore, there is a need for Pulmonary Rehabilitation (PR) where the objective is to improve the physical and mental conditions of the patient . The following case report aims to describe the progression of a patient hospitalized with hypoxaemia due to the sequelae of COVID-19 pneumonia, who underwent PR to achieve weaning from oxygen and to return home . Male patient, 79 years old, with COVID-19 and bilateral pneumonia who required hospitalization for 28 days . After 15 days of hospitalization, he had developed muscle weakness and high oxygen requirements, and therefore began a PR programme . At 28 days, he was discharged with oxygen . The fourth week after starting rehabilitation, he is able to disconnect from oxygen and continue his outpatient rehabilitation . Patients with Covid-19 with bilateral pneumonia with hypoxaemia should start a PR programme early to avoid or limit the physical and emotional deterioration of the patient.