Objective: In Taiwan, the overall incidence of acute respiratory distress syndrome (ARDS) is 15.74 per 100,000 person-years, the mortality rate is 57.8%, and its overall prevalence in the intensive care unit (ICU) is 10.4% . Women who are pregnant and have ARDS have a high risk of fetal death and fetal asphyxia . Case report: A 26-1/7-week pregnant woman presented with upper respiratory infection symptoms progressing to ARDS . While receiving ventilation, maintaining a prone position is an option for pregnant patients with severe ARDS. This case demonstrated a supplementary approach for pregnant women with ARDS. Conclusion: Prone position ventilation is indicated for pregnant women, as for any patient with ARDS . The Proning Severe ARDS Patients trial showed no difference in the complication between pregnant patients and other groups.