By 31 December 2020, Coronavirus disease 2019 (COVID-19) had been prevalent worldwide for one year, and most countries had experienced a complete seasonal cycle . The role of the climate and environment are essential factors to consider in transmission.We explored the association between global meteorological conditions (including mean temperature, wind speed, relative humidity and diurnal temperature range) and new cases of COVID-19 in the whole past year . We assessed the relative risk of meteorological factors to the onset of COVID-19 by using generalized additive models (GAM) and further analyzed the hysteresis effects of meteorological factors using the Distributed Lag Nonlinear Model (DLNM) .Our findings revealed that the mean temperature, wind speed and relative humidity were negatively correlated with daily new cases of COVID-19, and the diurnal temperature range was positively correlated with daily new cases of COVID-19 . These relationships were more apparent when the temperature and relative humidity were lower than their average value (21.07°Cand 66.83 %). The wind speed and diurnal temperature range were higher than the average value (3.07 m/s and 9.53 °C). The maximum RR of mean temperature was 1.30 under −23 °C at lag ten days, the minimum RR of wind speed was 0.29 under 12 m/s at lag 24 days, the maximum RR of range of temperature was 2.21 under 28 °C at lag 24 days, the maximum RR of relative humidity was 1.35 under 4% at lag 0 days . After a subgroup analysis of the countries included in the study, the results were still robust.As the Northern Hemisphere enters winter, the risk of global covid-19 remains high . Some countries have ushered in a new round of COVID-19 epidemic . Thus, active measures must be taken to control the source of infection, block transmission and prevent further spread of COVID-19 in winter.