Introduction: Since the worldwide emergence of the COVID-19, several protocols were used by different healthcare organisations . We evaluated in this study the demographic and clinical characteristics of COVID-19 disease in Egyptian population with special consideration for its mortality predictors . Methodology: 8162 participants (mean age 48.7 years,54.5% males) with RT-PCR positive COVID-19 were included . The electronic medical records were reviewed for demographic, clinical, laboratory, and radiologic features . The primary outcome was the in-hospital mortality rate .
Results: The in-hospital mortality was 11.2% . There was a statistically significant strong association of in-hospital mortality with age> 60 years old (OR:4.7; 95% CI 4.1-5.4; p <0.001), diabetes mellitus (OR:4.6; 95% CI 3.99-5.32; p <0.001), hypertension (OR:3.9; 95% CI 3.4-4.5; p <0.001), coronary artery disease (OR:2.7; 95% CI 2.2-3.2; p <0.001), chronic obstructive pulmonary disease (OR:2.1; 95% CI 1.7-2.5; p <0.001), chronic kidney disease (OR:4.8; 95% CI 3.9-5.9; p <0.001), malignancy (OR:3.7; 95% CI 2.3-5.75; p <0.001), neutrophil-lymphocyte ratio> 3.1 (OR:6.4; 95% CI 4.4-9.5; P <0.001), and ground glass opacities (GGOs) in CT chest (OR:3.5; 95% CI 2.84-4.4; P <0.001), respectively . There was a statistically significant moderate association of in-hospital mortality with male gender (OR:1.6; 95% CI 1.38-1.83; p <0.001) and smoking (OR:1.6; 95% CI 1.3-1.9; p <0.001). GGOs was reported as the most common CT finding (occurred in 73.1% of the study participants).
Conclusions: This multicenter, retrospective study ascertained the higher in-hospital mortality rate in Egyptian COVID-19 patients with different comorbidities.