The COVID-19 pandemic has prompted widespread primary and secondary school closures . Routine testing of asymptomatic students and staff, as part of a comprehensive program, can help schools open safely .``Pooling-in-a-pod"is a public health surveillance strategy whereby testing cohorts are composed based on social relationships and physical proximity . Pooling-in-a-pod allowed for weekly on-site point-of-care testing of all staff and students at an independent preschool to grade 12 school in Washington, D.C. Staff and older students self-collected anterior nares samples, and trained staff collected samples from younger students . Overall , 6,746 samples were tested for 815 students and 276 staff between November 30 , 2020, and March 3 , 2021 . The average pool size was 7.3 people . Sample collection to pool result time averaged 40 minutes . The direct testing cost per person per week was $24.77, including swabs . One surveillance test pool was positive . During the study period, daily new cases in Washington, D.C., ranged from 24 - 46 per 100,000 population . A post-launch survey found most parents (90.3 %), students (93.4 %), and staff (98.8 %) were willing to participate in pooled testing with confirmatory tests for positive pool members . The school reported a 32.6% decrease in virtual learning after initiation of the program . Pooling-in-a-pod is feasible, cost-effective, and an acceptable COVID-19 surveillance strategy for schools . School officials and policymakers can leverage this strategy to facilitate safe, sustainable, in-person schooling.