The COVID-19 pandemic has resulted in an unprecedented strain on every aspect of the healthcare system, and clinical research is no exception . Researchers are working against the clock to ramp up research studies addressing every angle of COVID-19 - gaining a better understanding of person-to-person transmission, improving methods for diagnosis, and developing therapies to treat infection and vaccines to prevent it . The impact of the virus on research efforts is not limited to investigators and their teams . Potential participants also face unparalleled opportunities and requests to participate in research, which can result in a significant amount of participant fatigue . The Vanderbilt Institute for Clinical and Translational Research recognized early in the pandemic that a solution to assist researchers in the rapid identification of potential participants was critical, and thus developed the COVID-19 Recruitment Data Mart . This solution does not rest solely on technology; the addition of experienced project managers to support researchers and facilitate collaboration was essential . Since the platform and study support tools were launched on July 20 , 2020, four studies have been onboarded and a total of 1693 potential participant matches have been shared . Each of these patients had agreed in advance to direct contact for COVID-19 research and had been matched to study-specific inclusion/exclusion criteria . Our innovative Data Mart system is scalable and looks promising as a generalizable solution for simultaneously recommending individuals from a pool of patients against a pool of time-sensitive trial opportunities.