The dynamics of immune responses in asymptomatic SARS-CoV-2-infected subjects remain to be fully characterized . The work presented in this issue of JEM by Le Bert et al . (2021 . J. Exp . Med.https: //doi.org/10.1084/jem.20202617) sheds some light on these issues and ultimately provides some degree of confidence in the magnitude and persistence of immunity over time after asymptomatic infection with SARS-CoV-2.