The COVID-19 pandemic has had negative effects on health-care workers . The rapid growth of the disease has led to overwhelmed health-care systems, overcrowded hospitals, an insufficient number of health-care professionals and shortages of medical equipment . The potential exposure of front-line health-care workers during the COVID-19 outbreak has led to self-isolation and the appearance of adverse feelings such as stress, anxiety and fear . All these factors, combined with an increased workload and extra and changed shifts, are determinants of a sleep-loss process that may result in insomnia . The exacerbated pro-inflammatory milieu caused by insomnia and sleep deprivation present in health professionals may therefore make them more prone to developing severe COVID-19 if infected and/or aggravate the symptoms of the disease . Keeping these professionals healthy and doing everything possible to prevent them from being infected with COVID-19 should be a top priority . As part of this effort, we must be aware of the important effects of insomnia on the immune systems of these professionals and take all possible measures to counter these effects.