Since December 2019, the havoc caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has increased exponentially in a short period of time . As the COVID-19 pandemic is raging around the world, scientists are trying to reveal its mysteriousness . Although COVID-19 is predominantly a respiratory disease, the most common symptoms are fever, dry cough, and fatigue, but extrapulmonary manifestations are increasingly recognized . Recent studies have shown that there is a strong genetic correlation between one or more psychiatric disorders and the occurrence of SARS-CoV-2 infection . Historical epidemiological perspectives and recent neurobiological evidence link infection and psychosis . What is the relationship between COVID-19 and psychiatric disorders? In this article, we will review the correlation between COVID-19 and psychoses, the possible reasons, and the possible pathophysiological mechanisms . The purpose of this review is to provide a reference for clinicians to make correct judgment and treatment when facing patients with COVID-19 and/or psychiatric disorders.