BACKGROUND: Specific details about cardiovascular complications, especially arrhythmias, related to the coronavirus disease of 2019 (COVID-19) are not well described .
OBJECTIVE: We sought to evaluate the incidence and predictive factors of cardiovascular complications and new-onset arrhythmias in Black and White hospitalized COVID-19 patients and determine the impact of new-onset arrhythmia on outcomes .
METHODS: We collected and analyzed baseline demographic and clinical data from COVID-19 patients hospitalized at the Tulane Medical Center in New Orleans, Louisiana, between March 1 and May 1 , 2020 .
RESULTS: Among 310 hospitalized COVID-19 patients, the mean age was 61.4 ± 16.5 years, with 58,7% females, and 67% Black patients . Black patients were more likely to be younger, have diabetes and obesity . The incidence of cardiac complications was 20%, with 9% of patients having new-onset arrhythmia . There was no significant difference in cardiovascular outcomes between Black and White patients . A multivariate analysis determined age & #8805; 60 years to be a predictor of new-onset arrhythmia (OR = 7.36 , 95% CI [1.95; 27.76], p = .003). D-dimer levels positively correlated with cardiac and new-onset arrhythmic event . New onset atrial arrhythmias predicted in-hospital mortality (OR = 2.99 95% CI [1.35; 6.63], p = .007), a longer intensive care unit length of stay (mean of 6.14 days , 95% CI [2.51; 9.77], p = .001) and mechanical ventilation duration (mean of 9.08 days , 95% CI [3.75; 14.40], p = .001).
CONCLUSION: Our results indicate that new onset atrial arrhythmias are commonly encountered in COVID-19 patients and can predict in-hospital mortality . Early elevation in D-dimer in COVID-19 patients is a significant predictor of new onset arrhythmias . Our finding suggest continuous rhythm monitoring should be adopted in this patient population during hospitalization to better risk stratify hospitalized patients and prompt earlier intervention.