Objective: There has been a substantial decline in patients presenting for emergent and routine cardiovascular care in the United States after the onset of the coronavirus disease 2019 (COVID-19) pandemic . We sought to assess the risk of adverse clinical outcomes among patients undergoing coronary artery bypass graft (CABG) surgery during the 2020 COVID-19 pandemic period and compare the risks with those undergoing CABG before the pandemic in the year 2019 .
Methods: A retrospective cross-sectional analysis of the TriNetX Research Network database was performed . Patients undergoing CABG between January 20 , 2019, and September 15 , 2019, contributed to the 2019 cohort, and those undergoing CABG between January 20 , 2020, and September 15 , 2020, contributed to the 2020 cohort . Propensity-score matching was performed, and the odds of mortality, acute kidney injury, stroke, acute respiratory distress syndrome, and mechanical ventilation occurring by 30 days were evaluated .
Results: The number of patients undergoing CABG in 2020 declined by 35.5% from 5534 patients in 2019 to 3569 patients in 2020 . After propensity-score matching , 3569 patient pairs were identified in the 2019 and the 2020 cohorts . Compared with those undergoing CABG in 2019, the odds of mortality by 30 days were 0.96 (95% confidence interval [CI], 0.69-1.33; P = .80) in those undergoing CABG in 2020 . The odds for stroke (odds ratio [OR], 1.201; 95% CI , 0.96-1.39), acute kidney injury (OR , 0.76; 95% CI , 0.59-1.08), acute respiratory distress syndrome (OR , 1.01; 95% CI , 0.60-2.42), and mechanical ventilation (OR , 1.11; 95% CI , 0.94-1.30) were similar between the 2 cohorts .
Conclusions: The number of patients undergoing CABG in 2020 has substantially declined compared with 2019 . Similar odds of adverse clinical outcomes were seen among patients undergoing CABG in the setting of COVID-19 compared with those in 2019.