BACKGROUND: Filling a prescription on the web has become an alternative to in-person pharmacies for individuals to access their medications . However, the adoption of web-based filling has been gradual, and the use patterns remain to be unclear .
OBJECTIVE: This study aims to estimate the trend and prevalence of web-based prescription-filling behavior and identify associated factors among adults in the United States .
METHODS: We used data from the US National Health Interview Survey (NHIS) from 2009 to 2018 . Adult respondents (aged & #8805; 18 years and over) self-reported their behavior of web-based prescription filling, which was defined as having filled a prescription using the internet in the past 12 months during the survey year . We reported trends using weighted percentages adjusted by the NHIS complex sampling design . We used descriptive statistics and multivariable logistic regression models to examine trends and identify factors associated with web-based prescription-filling behavior .
RESULTS: The estimated number of adults reporting web-based prescription-filling behavior significantly increased from 13,319,877 (13,319,877/225,217,942 , 5.91 %) in 2009 to 28,308,262 (28,308,262/246,611,125 , 11.48 %) in 2018 (P <.001). Those who were more likely to report filling a prescription on the web were aged between 35 and 74 years, female, White, and frequent users of the computer or internet; these adults also reported higher education, higher income, insurance coverage, and poorer health status .
CONCLUSIONS: Web-based prescription-filling behavior among US adults has increased significantly from 2009 to 2018 . Health care providers should be aware of the upward trend in the use of web-based pharmacies and ensure the clinical safety of web-based prescriptions.