Assessing knowledge, attitude, and practices of healthcare students regarding any infectious outbreak became a fundamental step to set an effective plan related to their preparedness . The purpose of this study was to assess COVID-19 knowledge, attitude, and precautionary practices among health professional students in Oman . Data were collected using the Web-based survey method . The sample was recruited from the largest college of Medicine in Oman, while the nursing sample was recruited from two different nursing colleges in Oman . The study tool was developed based on the most recent advisory COVID-19 recommendations from the WHO and the CDC . A total of 222 students filled the survey, of which 55% were medical students and 59.9% were females . The mean knowledge score was 16.5 (SD = 4.2), which represents 66% of the highest possible score, with 25.7% were classified as 'excellent knowledge' . Participants reported a high level of public precautionary practices (M = 44.1, SD = 5.0), which represents 84.6% of the highest score, with 61.3% were classified as 'high compliance . The mean attitude score was 40.3 (SD = 5.9), which represents 67% of the highest possible score . According to the classification categories, most students (81%, n = 180) expressed a positive attitude toward COVID-19 . More efforts should be done toward preparing the healthcare students to deal with the outbreak . Preparing healthcare students with the right knowledge, attitude, and precautionary practices during the COVID-19 outbreak is very essential to patient and public safety . Healthcare students can play a major role in increasing public awareness about COVID-19 precautionary practices.